Research & Publications

Research Projects

COSMIN is involved in many research projects and is continually developing new tools and publishing about selecting outcome measurement instruments.

COSMIN for clinician-reported and performance-based outcome measures

The COSMIN checklist was developed for assessing the quality of studies on the measurement properties of patient-reported outcome measures (PROMs), and should be adapted for assessing the quality of studies on measurement properties of clinician-reported (ClinROMs) and performance-based outcome measure (PerBOMs) which are typically more complex, requiring strict protocols, specific equipment and involvement of personnel.

The aim of this project is to develop an adapted COSMIN Risk of Bias checklist, for conducting systematic reviews of clinician reported and performance based outcome measurement instruments. We will perform an international Delphi study among experts from various biomedical fields to reach consensus on the methodology and Risk of Bias checklist.

This study is funded by ZonMw (The Netherlands Organisation for Health Research and Development).

Simulation study to determine sample size requirements for reliability studies

A series of simulation studies will be performed to generate more evidence on sample size requirements for reliability studies. Aim is to develop standards for how many participants and raters are needed to obtain Intraclass Correlation Coefficient estimates with sufficient precision in a variety of designs.

The simulation studies will be based on realistic clinical examples, involving different sources of variation in the reliability studies. The goal is to examine the influence of the most important factors on the required sample size, like the number of observers, the number of objects that need to be rated (e.g. patients), the expected ICC or kappa value, and whether the design is complete (i.e. all objects are rated by all observers) or incomplete (i.e. the objects are only rated by a subset from all observers).

This study is funded by ZonMw (The Netherlands Organisation for Health Research and Development).

COSMIN Reporting checklist for studies on measurement properties of patient-reported outcome measures

In collaboration with the University of Michigan, Ann Arbor, MI, USA, we are developing the COSMIN Reporting checklist. By creating recommendations and specific guidance for the reporting of studies focusing on the measurement properties of PROMs, we aim to improve the completeness of the written information in studies on measurement properties and ultimately to improve the ability of researchers and clinicians to select the most suitable outcome measurement instrument for their purpose which will eventually improve the quality of outcome measurement in research and clinical practice.

This study is funded by Patient-Centered Outcomes Research Institute (PCORI)

Publications

Original publications

Prinsen CAC, Mokkink LB, Bouter LM, Alonso J, Patrick DL, de Vet HCW, Terwee CB. COSMIN guideline for systematic reviews of patient-reported outcome measures. Qual Life Res. 2018 May;27(5):1147-1157. doi: 10.1007/s11136-018-1798-3.

Terwee CB, Prinsen CAC, Chiarotto A, Westerman MJ, Patrick DL, Alonso J, Bouter LM, de Vet HCW, Mokkink LB. COSMIN methodology for evaluating the content validity of patient-reported outcome measures: a Delphi study. Qual Life Res. 2018 May;27(5):1159-1170. doi: 10.1007/s11136-018-1829-0.

Mokkink LB, de Vet HCW, Prinsen CAC, Patrick DL, Alonso J, Bouter LM, Terwee CB. COSMIN Risk of Bias checklist for systematic reviews of Patient-Reported Outcome Measures. Qual Life Res. 2018 May;27(5):1171-1179. doi: 10.1007/s11136-017-1765-4.

Prinsen CA, Vohra S, Rose MR, Boers M, Tugwell P, Clarke M, Williamson PR, Terwee CB. How to select outcome measurement instruments for outcomes included in a “Core Outcome Set” – a practical guideline. Trials. 2016 Sep 13;17(1):449. doi: 10.1186/s13063-016-1555-2.

Mokkink LB, Prinsen CA, Bouter LM, Vet HC, Terwee CB. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) and how to select an outcome measurement instrument. Braz J Phys Ther. 2016 Jan 19;20(2):105-13. doi: 10.1590/bjpt-rbf.2014.0143.

Terwee CB, Prinsen CAC, Ricci Garotti MG, Suman A, de Vet HCW, Mokkink LB. The quality of systematic reviews of health-related outcome measurement instruments. Quality of Life Research 2016;25(4):767-79.

Terwee CB, Mokkink LB, Knol DL, Ostelo RWJG, Bouter LM, de Vet HCW. Rating the methodological quality in systematic reviews of studies on measurement properties: a scoring system for the COSMIN checklist. Quality of Life Research 2012;21(4):651-7.

Mokkink LB, Terwee CB, Patrick DL, Alonso J, Stratford PW, Knol DL, Bouter LM, de Vet HCW. International consensus on taxonomy, terminology, and definitions of measurement properties for health-related patient-reported outcomes: results of the COSMIN study. Journal of Clinical Epidemology 2010;63:737-745. doi: 10.1016/j.jclinepi.2010.02.006.

Mokkink LB, Terwee CB, Patrick DL, Alonso J, Stratford PW, Knol DL, Bouter LM, de Vet HCW. The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study. Quality of Life Research 2010;19:539-549. doi: 10.1007/s11136-010-9606-8.

Mokkink LB, Terwee CB, Knol DL, Stratford PW, Alonso J, Patrick DL, Bouter LM, de Vet HCW. The COSMIN checklist for evaluating the methodological quality of studies on measurement properties: A clarification of its content. BMC Medical Research Methodology 2010;10:22. doi: 10.1186/1471-2288-10-22.

Mokkink LB, Terwee CB, Gibbons E, Stratford PW, Alonso J, Patrick DL, Knol DL, Bouter LM, de Vet HCW. Inter-rater reliability of the COSMIN (COnsensus-based Standards for the selection of health status Measurement Instruments) Checklist. BMC Medical Research Methodology 2010;10:82. doi: 10.1186/1471-2288-10-82.

Mokkink LB, Terwee CB, Stratford PW, Alonso J, Patrick DL, Riphagen I, Knol DL, Bouter LM, de Vet HCW. Evaluation of the methodological quality of systematic reviews of health status measurement instruments. Quality of Life Research 2009;18:313-333. doi: 10.1007/s11136-009-9451-9.

Terwee CB, Jansma EP, Riphagen II, de Vet HC. Development of a methodological PubMed search filter for finding studies on measurement properties of measurement instruments. Qual Life Res. 2009 Oct;18(8):1115-23. doi: 10.1007/s11136-009-9528-5.

Mokkink LB, Terwee CB, Knol DL, Stratford PW, Alonso J, Patrick DL, Bouter LM, de Vet HCW. Protocol of the COSMIN study: COnsensus-based Standards for the selection of health Measurement INstruments. BMC Medical Research Methodology 2006;6:2.

Comments & Letters to editors

Terwee CB, Mokkink LB, Hidding LM, Altenburg TM, van Poppel MN, Chinapaw MJ. Comment on “Should we reframe how we think about physical activity and sedentary behavior measurement? Validity and reliability reconsidered”. Int J Behav Nutr Phys Act. 2016 Jun 10;13:66. doi: 10.1186/s12966-016-0392-8.

Mokkink LB, Terwee CB, Prinsen CA, de Vet HC; COSMIN Steering Committee. Taxonomy of measurement properties: A commentary on Polit (2015). Int J Nurs Stud. 2016 Jan;53:399-400. doi: 10.1016/j.ijnurstu.2015.08.010.

Terwee CB, de Vet HCW, Mokkink LB. Reply to “COSMIN for quality rating systematic reviews on psychometric properties”. Accepted Physical Therapy Reviews Juni 2015.

Mokkink LB, Terwee CB, Knol DL, de Vet HCW. The new COSMIN guidelines regarding responsiveness. Author’s response. BMC Med Res Methodol 2011;11:152.

Comment on “Checklist to operationalize measurement characteristics of patient-reported outcome measures”

Francis DO, McPheeters ML, Noud M, Penson DF, Feurer ID. Checklist to operationalize measurement characteristics of patient-reported outcome measures. Syst Rev 2016;5(1):129.

Other publications:

Francis DO, McPheeters ML, Noud M, Penson DF, Feurer ID. Checklist to operationalize measurement characteristics of patient-reported outcome measures. Syst Rev 2016;5(1):129.

Copyright and permission to use COSMIN materials

How to use COSMIN materials

COSMIN materials on this site may be reproduced in whole or in part in any form for educational or non-profit purposes without special permission from VUmc, provided acknowledgement of the source is made. No use may be made for resale or for any other commercial purposes whatsoever withour prior permission in writing from VUmc. enquiries should be addressed to VUmc at the address noted below:

p/a LB Mokkink,

dept of Epidemiology and Biostatistics,

VUmc, F-vleugel medische faculteit,

De Boelelaan 1089a,

1081 HV Amsterdam, the Netherlands